Formulation:

Bisacodyl 5 mg per tablet

Indication/s

Indicated for the relief of occasional constipation and irregular bowel movements in adults and children over 10 years of age. It is also used to prepare the bowel before medical examinations or surgery.

Contraindication/s

Hypersensitivity to bisacodyl or any of the tablet’s components

Dosage and Administration

Use this medicine as prescribed by your doctor

Special Instructions

• Use Dulcolax® for short-term relief only; do not use for more than 5 consecutive days.
• Consult a healthcare provider if constipation persists or worsens.
• Overuse may lead to dependence, dehydration, and electrolyte imbalances.
• Not intended for weight loss purposes.

Storage Condition

Store below 25°C. Protect from humidity. Keep out of reach of children.

Mechanism of Action

• The enteric coating protects bisacodyl from stomach acid; it’s activated in the colon.
• Stimulation of Bowel: The active form stimulates bowel muscles and increases water secretion, promoting bowel movements.
• Localized Action: Acts directly in the colon with minimal absorption into the bloodstream.

Formulation

• Sodium Picosulfate: 10 mg
• Magnesium Oxide: 3.5 g
• Citric Acid: 12 g

Indication/s

PicoPrep® is indicated for bowel cleansing prior to:

• Colonoscopy
• Abdominal X-ray examinations
• Surgical procedures involving the gastrointestinal tract

Contraindication/s

Hypersensitivity to any of the ingredients

Storage Condition

Store at temperatures not exceeding 25°C

Dosage and Administration

Use this medicine as prescribed by your doctor

Special Instructions

• Consult your doctor before using DUPHALAC® if you have heart conditions or other underlying health issues.
• Monitor for side effects such as diarrhea, abdominal discomfort, or electrolyte imbalances.
• Regular medical check-ups are advisable during prolonged use.

Mechanism of Action

• The stimulant and osmotic actions work together to induce bowel movements, effectively cleansing the colon

Indication/s

• Constipation: regulation of the physiological rhythm of the colon
• Where a soft stool is considered of medical benefit (hemorrhoids, post colonic/anal surgery)
• Hepatic Encephalopathy (HE): treatment and prevention of hepatic coma or precoma (adults)
• For bowel cleansing in preparation for colonoscopy (adults)
• As a prebiotic, helps create and maintain a healthy intestinal balance and stimulates intestinal absorption of minerals like calcium and magnesium (adults)

Contraindication/s

• Hypersensitivity to the active substance or ingredients
• Galactosemia
• Gastrointestinal obstruction, digestive perforation, or risk thereof
• Should not be used for bowel cleansing in unconscious patients or those with aspiration risk, severe dehydration, or swallowing issues

Storage Condition

Store at temperatures not exceeding 25°C. Protect from light.

Dosage and Administration

Adults and Adolescents (≥14 years):

• Starting dose: 15–45 mL per day
• Maintenance dose: 15–30 mL per day

Children (7–14 years):

• Starting dose: 15 mL per day
• Maintenance dose: 10–15 mL per day

Children (1–6 years):

• Usual dose: 5–10 mL per day

Infants (<1 year):

• Usual dose: Up to 5 mL per day

Special Instructions

• Administer with care to lactose-intolerant patients
• Usual constipation doses are safe for diabetics; HE doses may need caution
• Chronic misuse can cause diarrhea and electrolyte imbalance
• Contains lactose, galactose, and fructose — avoid in hereditary intolerance cases
• Refer to the patient leaflet for complete prescribing information

Mechanism of Action

• Draws water into the colon to soften stool and promote bowel movement
• Reduces blood ammonia by converting NH₃ to NH₄⁺ in the colon
• Metabolized by gut bacteria into SCFAs to lower pH and enhance laxative effect